Plastic and Reconstructive Surgery

Skip Navigation LinksHome > August 2013 - Volume 132 - Issue 2 > Analgesic Efficacy of Lidocaine for Suction-Assisted Lipecto...
Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e3182958b20
Cosmetic: Original Articles

Analgesic Efficacy of Lidocaine for Suction-Assisted Lipectomy with Tumescent Technique under General Anesthesia: A Randomized, Double-Masked, Controlled Trial

Danilla, Stefan M.D., M.Sc.; Fontbona, Montserrat M.D.; de Valdés, Victoria Diaz M.D.; Dagnino, Bruno M.D.; Sorolla, Juan Pablo M.D.; Israel, Guillermo M.D.; Searle, Susana M.D.; Norambuena, Hernán M.D.; Cabello, Rodrigo M.D.

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Background: Suction-assisted lipectomy is one of the most common procedures performed in plastic surgery. To minimize blood loss and to obtain adequate analgesia, a liquid solution is infiltrated into the subcutaneous plane before suction. The objective of this study was to determine whether the use of lidocaine in the infiltration solution reduces postoperative pain.

Methods: A prospective, randomized, double-masked, clinical trial was designed. Each side of patients’ body zones to be treated with suction-assisted lipectomy was randomized to receive infiltration solution with or without lidocaine. Treatment allocation was performed using computer-generated random numbers in permuted blocks of eight. Pain was assessed using the visual analogue scale and registered 1, 6, 12, 18, and 24 hours after the procedure.

Results: The trial was stopped after a first interim analysis. The use of lidocaine in the dilute solution reduced pain by 0.5 point on the visual analogue scale (95 percent CI, 0.3 to 0.8; p < 0.001). The effect was independent of the suctioned body zone (p = 0.756), and lasted until 18 hours after surgery. Its analgesic effect was lost at the 24-hour postoperative control. Pain increased an average of 0.018 point on the visual analogue scale per hour (95 percent CI, 0.001 to 0.036; p = 0.043).

Conclusions: The use of lidocaine in the infiltration solution is effective in postoperative pain control until 18 hours after surgery. Nevertheless, its clinical effect is limited and clinically irrelevant, and therefore it is no longer used by the authors.


©2013American Society of Plastic Surgeons


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