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Facial Soft-Tissue Fillers Conference: Assessing the State of the Science

Rohrich, Rod J. M.D.; Hanke, C. William M.D.; Busso, Mariano M.D.; Carruthers, Alastair M.A., B.M., B.Ch.; Carruthers, Jean M.D.; Fagien, Steven M.D.; Fitzgerald, Rebecca M.D.; Glogau, Richard M.D.; Greenberger, Phyllis E. M.S.W.; Lorenc, Z. Paul M.D.; Marmur, Ellen S. M.D.; Monheit, Gary D. M.D.; Pusic, Andrea M.D., M.H.S.; Rubin, Mark G. M.D.; Rzany, Berthold M.D., Sc.M.; Sclafani, Anthony M.D.; Taylor, Susan M.D.; Weinkle, Susan M.D.; McGuire, Michael F. M.D.; Pariser, David M. M.D.; Casas, Laurie A. M.D.; Collishaw, Karen J.; Dailey, Roger A. M.D.; Duffy, Stephen C.; Edgar, Elizabeth Jan M.S.; Greenan, Barbara L.; Haenlein, Kelly M.H.A.; Henrichs, Ronald A. C.A.E.; Hume, Keith M. M.A.; Lum, Flora M.D.; Nielsen, David R. M.D.; Poulsen, Lisle; Schoaf, Lori J.D.; Seward, William M.A.; Begolka, Wendy Smith M.S.; Stanton, Robert G.; Svedman, Katherine J. C.A.E.; Thomas, J. Regan M.D.; Sykes, Jonathan M. M.D.; Wargo, Carol M.A.; Weiss, Robert A. M.D.

Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e31820578d0
Facial Soft-Tissue Fillers Supplement: Literature Review
Abstract

Summary: The American Society of Plastic Surgeons and the American Academy of Dermatology, with the support of other sister societies, conducted the Facial Soft-Tissue Fillers: Assessing the State of the Science conference in December of 2009. The American Society of Plastic Surgeons and the American Academy of Dermatology established a panel of leading experts in the field of soft-tissue fillers—from researchers to clinicians—and other stakeholders for the conference to examine and discuss issues of patient safety, efficacy, and effectiveness in relation to the approved and off-label use of soft-tissue fillers, and other factors, including the training and level of experience of individuals administering fillers. This report represents the systematic literature review that examines comprehensively the available evidence and gaps in the evidence related to soft-tissue fillers, to inform and support the work of the state-of-the-science conference panel. This evidence-based medicine review will serve as the foundation for future evidence-based medicine reports in this growing field.

In Brief

APPENDICES TO THIS ARTICLE ARE AVAILABLE ONLINE.

Author Information

Dallas, Texas; and Carmel, Ind.

From the Department of Plastic Surgery, University of Texas Medical Center, and the Department of Dermatology, Saint Vincent Carmel Medical Center, Laser and Skin Surgery Center of Indiana.

Received for publication May 25, 2010; revised November 5, 2010.

Prepared for the American Society of Plastic Surgeons and the American Academy of Dermatology by The Lewin Group.

Disclosures: Rod J. Rohrich, M.D., declares he is the recipient of research grant funds received by the University of Texas Southwestern Medical Center from Medicis, Contura, Mentor (dermal fillers or botulinum toxin type A studies), and Baxter (fibrin sealant study). C. William Hanke, M.D., declares financial interest as a shareholder in Medicis and Allergan. In addition, he declares having been the recipient of research support from Medicis, Allergan, Merz, Dermik, and Galderma. For additional disclosure information, please see the Disclosure Appendix in this issue.

This supplement in its entirety is jointly published by the Journal of the American Academy of Dermatology and Plastic and Reconstructive Surgery.

Citation of the articles in PRS follows this format:

Rohrich RJ, Hanke CW. Facial Soft-Tissue Fillers: Assessing the State-of-the-Science Conference—Proceedings Report. Plast Reconstr Surg. 2011;127(Suppl 2):9S–21S.

Citation of the articles in JAAD follows this format:

Hanke CW, Rohrich RJ, Busso M, Carruthers A, Carruthers J, Fagien S, et al. Facial Soft-Tissue Fillers: Assessing the State-of-the-Science Conference—Proceedings Report. J Am Acad Dermatol 2011;64(Suppl):S53–S65.

Please go to the online version of the Journal at www.PRSJournal.com and log in to access the online-only Appendices.

Rod J. Rohrich, M.D., Department of Plastic Surgery, University of Texas Southwestern Medical Center, 1801 Harry Hines Boulevard, Dallas, Texas 75390-9132, rjreditor_prs@plasticsurgery.org

C. William Hanke, M.D., Department of Dermatology, Saint Vincent Carmel Medical Center, Laser & Skin Surgery Center of Indiana, 13400 North Meridian Street, Suite 290, Carmel, Ind. 46032, cwmhanke@thelassi.com

©2011American Society of Plastic Surgeons