Plastic and Reconstructive Surgery

Skip Navigation LinksHome > December 2010 - Volume 126 - Issue 6 > Basic Science Review on Adipose Tissue for Clinicians
Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e3181f44790
Experimental: Scientific Review

Basic Science Review on Adipose Tissue for Clinicians

Brown, Spencer A. Ph.D.; Levi, Benjamin M.D.; Lequex, Charlotte; Wong, Victor W. M.D.; Mojallal, Ali M.D.; Longaker, Michael T. M.D., M.B.A.

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Summary: The recognition that fat contains stem cells has driven further examination into the potential uses of fat and adipose-derived stem cells in a wide number of clinical situations. New information about the harvesting, isolation, and subsequent differentiation properties of isolated adipose-derived stem cells has led to new research into novel tissue-engineered constructs and the transformation of adipose-derived stem cells to induced pluripotent stem cells. Clinically, use of fat grafts and adipose-derived stem cells worldwide and in the United States has dramatically increased in parallel to questions concerning the safety and efficacy of adipose-derived stem cell–based treatments. Currently, the U.S. Food and Drug Administration has not approved the use of isolated adipose-derived stem cells for medical indications.

©2010American Society of Plastic Surgeons


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