Novel tissue- and organ-engineering strategies are needed to address the growing need for replacement biological parts. Collective progress in stem cell technology, biomaterials, engineering, and molecular medicine has advanced the state of regenerative medicine, yet many hurdles to clinical translation remain. Plastic surgeons are in an ideal position to capitalize on emerging technologies and will be at the forefront of transitioning basic science research into the clinical reconstructive arena. This review highlights fundamental principles of bioengineering, recent progress in tissue-specific engineering, and future directions for this exciting and rapidly evolving area of medicine.
From the Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University.
Received for publication December 23, 2009; accepted February 24, 2010.
Disclosure: The authors have no financial interest in any of the products or devices mentioned in this article.
Geoffrey C. Gurtner, M.D., 257 Campus Drive, GK-201, Stanford, Calif. 94305, firstname.lastname@example.org