Plastic and Reconstructive Surgery

Skip Navigation LinksHome > August 2010 - Volume 126 - Issue 2 > A Guide to Organizing a Multicenter Clinical Trial
Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e3181df64fa
Hand/Peripheral Nerve: Outcomes Article

A Guide to Organizing a Multicenter Clinical Trial

Chung, Kevin C. M.D., M.S.; Song, Jae W. M.D.; WRIST Study Group

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Summary: Multicenter clinical trials are important research tools. Planning a multicenter clinical trial is a long and arduous task that requires substantial preparation time. In this guide, the authors discuss the steps used to plan a multicenter clinical trial. A preplanning phase, which involves formulating and refining a research question and conducting pilot studies, is detailed, and the planning phase, which involves the acquisition of funding to support the coordination and preparation of a multicenter clinical trial, culminating in the submission of an R01 grant, is described. An essential asset to planning a multicenter clinical trial is the fluidity with which all collaborators work together toward a common vision. The philosophy among collaborators should be consensus and commitment and is emphasized by the development of a consensus-assisted study protocol. Most important are the recruitment of centers and co-investigators who are dedicated, collaborative, and selfless in the team effort to achieve goals that cannot be reached by a single-center effort.

©2010American Society of Plastic Surgeons


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