Skip Navigation LinksHome > August 2008 - Volume 122 - Issue 2 > Comparative Study of Different Combinations of Microvascular...
Plastic & Reconstructive Surgery:
doi: 10.1097/PRS.0b013e31817d62c5
Experimental: Original Articles

Comparative Study of Different Combinations of Microvascular Anastomoses in a Rat Model: End-to-End, End-to-Side, and Flow-Through Anastomosis

Miyamoto, Shimpei M.D.; Okazaki, Mutsumi M.D.; Ohura, Norihiko M.D.; Shiraishi, Tomohiro M.D.; Takushima, Akihiko M.D.; Harii, Kiyonori M.D.

Collapse Box

Abstract

Background: This study aimed to compare several microvascular anastomotic techniques by patency rate using a free flap model in rats.

Methods: A microsurgical transfer model of a pectoral skin flap to the cervical region was used. In experiment 1, 120 rats were divided into four groups (n = 30 in each group) depending on the type of microvascular anastomotic technique. For group 1, end-to-end anastomoses were performed for arteries and veins. For group 2, end-to-side anastomoses were performed for arteries and end-to-end anastomoses were performed for veins. For group 3, flow-through anastomoses were performed for arteries and end-to-end anastomoses were performed for veins. For group 4, end-to-end anastomoses were performed for arteries and end-to-side anastomoses were performed for veins. Flap survival was assessed on day 3 and the success rates of the four groups compared. In experiment 2 (n = 10), postoperative blood flows of end-to-end and flow-through arterial anastomoses were measured.

Results: In experiment 1, the success rates in groups 1, 2, 3, and 4 were 76.7, 83.3, 100, and 83.3 percent, respectively. Differences between group 3 and the other groups were statistically significant. In experiment 2, the blood flow of flow-through arterial anastomosis (1.8 ml/minute) was much higher than that of end-to-end anastomosis (0.18 ml/minute).

Conclusions: Flow-through arterial anastomosis presented a higher blood flow through the anastomotic site, resulting in a higher success rate than conventional anastomoses. In veins, end-to-side anastomosis was equivalent to end-to-end anastomosis even though the diameter of the donor vein was larger than the recipient vein.

©2008American Society of Plastic Surgeons

Login

Article Tools

Share


The Clinical Masters of PRS – Breast eBooks
4 Essential eBooks for Plastic Surgeons