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Necrotizing Pneumonia in Children: Report of 41 Cases Between 2006 and 2011 in a French Tertiary Care Center

Lemaître, Chloé MD*†; Angoulvant, François MD‡§; Gabor, Flaviu MD; Makhoul, Juliette MD*; Bonacorsi, Stéphane MD, PhD†‖; Naudin, Jérôme MD**††; Alison, Marianne MD, PhD¶ ††; Faye, Albert MD, PhD; Bingen, Edouard PharmD, PhD†‖; Lorrot, Mathie MD, PhD

The Pediatric Infectious Disease Journal: October 2013 - Volume 32 - Issue 10 - p 1146–1149
doi: 10.1097/INF.0b013e31829be1bb
Brief Reports

Forty-one children hospitalized for necrotizing pneumonia were retrospectively analyzed. Necrotizing pneumonia represented 0.8% of community-acquired pneumonia and 6% of hospitalized community-acquired pneumonia. The chest radiograph revealed necrosis on admission in onethird of cases. Twenty-one cases (51%) were documented, including 13 Staphylococcus aureus, all Panton-Valentine leukocidin positive, 7 Streptococcus pneumoniae and 1 Fusobacterium nucleatum.

From the *General Pediatric Unit, APHP, Hôpital Robert-Debré; Univ Paris Diderot, Sorbonne Paris Cité; Pediatric Emergency Unit, APHP, Hôpital Robert-Debré; §Univ Paris Diderot, Sorbonne Paris Cité, Unité d’Épidémiologie Clinique INSERM CIE5; Radiologic Unit; Microbiologic Unit; **Pediatric Intensive Care Unit, APHP, Hôpital Robert-Debré; and ††Univ Paris Diderot, Sorbonne Paris Cité, Paris, France.

Accepted for publication May 14, 2013.

The authors have no funding or conflicts of interest to disclose.

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Address for correspondence: Mathie Lorrot, MD, PhD, Service de Pédiatrie Générale, Hôpital Robert-Debré, 48 Boulevard Sérurier, 75395 Paris Cedex 19, France. E-mail:

© 2013 by Lippincott Williams & Wilkins, Inc.