Institutional members access full text with Ovid®

Share this article on:

Would Parents Consent To A Comparative Effectiveness Trial Of Oral Doxycycline Versus Intravenous Ceftriaxone For The Treatment Of Children With Lyme Meningitis?.

Garro, Aris MD, MPH; Koster, Michael MD; LaRue, Molly BA; Hipolito, Evelyn BA; Congdon, Elizabeth BA; Burnett, Kathleen; Cullen, Nicole; Nigrovic, Lise E. MD, MPH
Pediatric Infectious Disease Journal: Post Acceptance: September 28, 2017
doi: 10.1097/INF.0000000000001793
Brief Reports: PDF Only

Children with Lyme meningitis are often treated with intravenous ceftriaxone although oral doxycycline may be effective. Parents were surveyed after observing a video describing a hypothetical Lyme meningitis treatment trial. Eighty-four of 102 (82%) would consent to their child participating. Parents would accept 2 additional days of symptoms (non-inferiority margin) with doxycycline even if ceftriaxone hastened symptom resolution.

Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.