We evaluated whether procalcitonin (PCT) might aid diagnosing serious bacterial infections in a general pediatric ICU population. 201 patients accounted for 332 PCT samples. A PCT >=1.45 ng/mL had a positive predictive value of 30%, a negative predictive value of 93%, and a sensitivity of 72% and a specificity of 75%. These data suggest PCT can assist in identifying patients without serious bacterial infections and limit antimicrobial use.
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