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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0000000000000370
Brief Reports: PDF Only

Procalcitonin Use in a Pediatric Intensive Care Unit.

Cies, Jeffrey J. PharmD, MPH, BCPS-AQ ID; Chopra, Arun MD

Published Ahead-of-Print
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Abstract

We evaluated whether procalcitonin (PCT) might aid diagnosing serious bacterial infections in a general pediatric ICU population. 201 patients accounted for 332 PCT samples. A PCT >=1.45 ng/mL had a positive predictive value of 30%, a negative predictive value of 93%, and a sensitivity of 72% and a specificity of 75%. These data suggest PCT can assist in identifying patients without serious bacterial infections and limit antimicrobial use.

(C) 2014 by Lippincott Williams & Wilkins, Inc.

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