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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3182678c19
HIV Reports: PDF Only

Prevalence of Transmitted HIV-1 Drug Resistance Mutations in Children and Adolescents in Sao Paulo, Brazil.

Almeida, Flávia Jacqueline MD; Rodrigues, Rosangela MD, PhD; Zaparoli, Mayra Simioni MSc; Berezin, Eitan Naaman MD, PhD; Sáfadi, Marco Aurélio Palazzi MD, PhD; de Paula Ferreira, João Leandro MSc; Lança, André Minhoto; de Macedo Brígido, Luis Fernando MD, PhD

Published Ahead-of-Print
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Abstract

HIV drug resistance genotype testing, performed on 39 HIV-infected treatment-naive children from 2000 to 2011, identified 5 children (12.8%) with drug resistance mutations (DRM): 5.3% to nucleoside reverse transcriptase inhibitors, 5.3% to non-nucleoside reverse transcriptase inhibitors and 7.7% to protease inhibitors. There was a trend for increasing prevalence of DRM during the 11 year study period.

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