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Pneumococcal Meningitis Before and After Universal Vaccination with Pneumococcal Conjugate Vaccines 7/13, Impact on Pediatric Hospitalization in Public and Non Public Institutions, in Uruguay.

Pírez, María Catalina MD; Mota, María Inés MD; Giachetto, Gustavo MD; Varela, Mercedes Sánchez MD; Galazka, Jeannette MD; Gutierrez, Stella MD; Varela, Adriana MD; Picón, Teresa MD; Algorta, Gabriela MD
Pediatric Infectious Disease Journal: Post Acceptance: June 28, 2017
doi: 10.1097/INF.0000000000001671
Vaccine Reports: PDF Only

This is the first study showing the impact of PCV13 on pneumococcal meningitis in Latin America; a significant (63.5%) reduction in hospitalization was observed during the first 6 years after starting vaccination. A 90% reduction of PCV7/13 serotypes was observed (p<0.0001). After vaccination, all strains were penicillin-susceptible. Mortality had a reduction of 71%.

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