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Parvovirus B19 Infection in a Fatal Case of Acute Liver Failure.

Leon, Luciane Amado PhD; Alves, Arthur MSc; Garcia, Rita Cubel PhD; Melgaço, Juliana PhD; de Paula, Vanessa PhD; Pinto, Marcelo PhD
Pediatric Infectious Disease Journal: Post Acceptance: August 2, 2017
doi: 10.1097/INF.0000000000001731
Brief Reports: PDF Only

B19V has been proposed as an etiologic agent for hepatitis, mainly in children, but this is a rare clinical occurrence. Here, we report a case of non-A-E acute liver failure (ALF) in an immunocompetent child with B19 infection. The clinical findings of severe anemia and pancytopenia combined with the detection of anti-B19 IgG, B19 DNA and B19 mRNA in liver indicate a persistent infection and suggest a diagnosis of parvovirus B19-associated ALF.

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