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Concomitant Bacterial Meningitis in Infants With Urinary Tract Infection

Thomson, Joanna MD, MPH*; Cruz, Andrea T. MD, MPH; Nigrovic, Lise E. MD, MPH; Freedman, Stephen B. MDCM, MSc§; Garro, Aris C. MD, MPH; Ishimine, Paul T. MD; Kulik, Dina M. MD**; Uspal, Neil G. MD††; Grether-Jones, Kendra L. MD‡‡; Miller, Aaron S. MD, MSPH§§; Schnadower, David MD, MPH¶¶; Shah, Samir S. MD, MSCE*‖‖; for the Pediatric Emergency Medicine Collaborative Research Committee (PEM CRC) HSV Study Group; Aronson, Paul L. MD; Balamuth, Fran MD, PhD

Pediatric Infectious Disease Journal: September 2017 - Volume 36 - Issue 9 - p 908–910
doi: 10.1097/INF.0000000000001626
Brief Reports

To determine age-stratified prevalence of concomitant bacterial meningitis in infants ≤60 days with a urinary tract infection, we performed a 23-center, retrospective study of 1737 infants with urinary tract infection. Concomitant bacterial meningitis was rare, but more common in infants 0–28 days of age [0.9%; 95% confidence interval (CI): 0.4%–1.9%) compared with infants 29–60 days of age (0.2%; 95% CI: 0%–0.8%).

From the *Division of Hospital Medicine, Cincinnati Children’s Hospital Medical Center and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio; Sections of Pediatric Emergency Medicine and Pediatric Infectious Diseases, Baylor College of Medicine, Houston, Texas; Division of Emergency Medicine, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts; §Sections of Pediatric Emergency Medicine and Gastroenterology, Alberta Children’s Hospital, Alberta Children’s Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Departments of Pediatrics and Emergency Medicine, Brown University and Rhode Island Hospital, Providence, Rhode Island; Division of Emergency Medicine, Rady Children’s Hospital, San Diego, California and Department of Emergency Medicine, University of California, San Diego; **Division of Pediatric Emergency Medicine, Hospital for Sick Children, Toronto, Ontario, Canada; ††Division of Emergency Medicine, Seattle Children’s Hospital, Seattle, Washington; ‡‡Department of Emergency Medicine, University of California, Davis Medical Center, Sacramento, California; §§Division of Pediatric Infectious Diseases, Cardinal Glennon Children’s Hospital, and ¶¶Division of Emergency Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri; and ‖‖Division of Infectious Disease, Cincinnati Children’s Hospital Medical Center and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio

Accepted for publication January 16, 2017.

The investigators listed in the acknowledgments section should also be designated as Collaborators in PubMed.

The network data center managed by Baylor College of Medicine was supported by the Section of Emergency Medicine, American Academy of Pediatrics (AAP) and Baylor College of Medicine.

S.B.F. is supported by the Alberta Children’s Hospital Foundation’s Professorship in Child Health and Wellness. The other authors have no conflicts of interest to disclose.

Address for correspondence: Joanna Thomson, MD, MPH, Division of Hospital Medicine, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave MLC 9016, Cincinnati, OH 45208. E-mail: Joanna.Thomson@cchmc.org.

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