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Tuberculosis Exposure, Infection and Disease Among Children with Medical Comorbidities

Cruz, Andrea T. MD, MPH*†‡; Merchant, Omar BS*; Zafar, Affan BS*; Starke, Jeffrey R. MD*†

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0000000000000343
Brief Reports

Sixty-nine children with medical comorbidities were treated for tuberculosis (TB) exposure (7), infection (40) or disease (22). The most common comorbidities in children with TB disease were malignancy (23%), cyanotic heart disease (18%), hemoglobinopathies (18%) and autoimmune disease (14%). Ninety-six percent who received TB medications had no adverse events and 98% completed therapy. Two (9%) died of TB.

Author Information

From the *Department of Pediatrics; Sections Infectious Diseases; and Emergency Medicine, Baylor College of Medicine, Houston, TX.

Accepted for publication March 6, 2014.

The authors have no funding or conflicts of interest to disclose.

Address for correspondence: Andrea T. Cruz, MD, MPH, 6621 Fannin Street, Suite A2210, Houston, TX 77030. E-mail:

© 2014 by Lippincott Williams & Wilkins, Inc.