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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0000000000000343
Brief Reports

Tuberculosis Exposure, Infection and Disease Among Children with Medical Comorbidities

Cruz, Andrea T. MD, MPH*†‡; Merchant, Omar BS*; Zafar, Affan BS*; Starke, Jeffrey R. MD*†

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Abstract

Sixty-nine children with medical comorbidities were treated for tuberculosis (TB) exposure (7), infection (40) or disease (22). The most common comorbidities in children with TB disease were malignancy (23%), cyanotic heart disease (18%), hemoglobinopathies (18%) and autoimmune disease (14%). Ninety-six percent who received TB medications had no adverse events and 98% completed therapy. Two (9%) died of TB.

Copyright © 2014 by Lippincott Williams & Wilkins

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