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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0000000000000213
Brief Reports

Characteristics and Outcomes OF Acute Otitis Media in Children Carrying Streptococcus Pneumoniae or Haemophilus Influenzae in Their Nasopharynx as a Single Otopathogen After Introduction of the Heptavalent Pneumococcal Conjugate Vaccine

Caeymaex, Laurence PhD*†; Varon, Emmanuelle MD; Levy, Corinne MD; Béchet, Stéphane§; Derkx, Véronique MD§; Desvignes, Véronique MD; Doit, Catherine MD; Cohen, Robert MD*†§

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After PCV7 implementation, clinical characteristics were investigated in 832 young children with acute otitis media, carrying a single S. pneumoniae or H. influenzae in their nasopharynx. As compared with H. influenzae, S. pneumoniae-associated acute otitis media was less frequently associated with treatment failure (odds ratio = 0.5; 95% confidence interval: 0.36–0.83) and recurrence (odds ratio = 0.4; 95% confidence interval: 0.22–0.75). Post-PCV7 serotype replacement seemed not to affect the acute otitis media characteristics in these children.

© 2014 by Lippincott Williams & Wilkins, Inc.


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