Adolescents with an immigrant background who are from tuberculosis high-incidence regions were at highest risk to develop adult-type tuberculosis disease in a low-incidence region during a 20-year period. If diagnosis and treatment were delayed up to 6 months, latent tuberculosis infection was detected in almost half of the affected individuals’ school contacts.
From the *Division of Infectious Diseases and Hospital Epidemiology, †Children’s Research Center, and ‡Division of Diagnostic Imaging, University Children’s Hospital of Zurich; §TB Zentrum bei Lunge Zürich, Lung League of the Canton of Zurich, Zurich; and ¶Federal Office of Public Health, Division of Communicable Diseases, Berne, Switzerland.
Accepted for publication September 13, 2013.
The authors have no funding or conflicts of interest to disclose.
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Address for correspondence: David Nadal, MD, Div. Infectious Diseases and Hospital Epidemiology, University Children’s Hospital, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland. E-mail: email@example.com.