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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0000000000000043
Brief Reports

The Clinical Burden And Predictors of Sequelae Following Invasive Meningococcal Disease In Australian Children

Wang, Bing MB BS*†; Clarke, Michelle AppSc(Med Lab), GDipSTC; Thomas, Natalie BHSc (Hons), LL.B, GDLP, MPH; Howell, Stuart BA (Hons), PhD§; Afzali, Hossein Haji Ali GDPH, MD, PhD; Marshall, Helen MB BS, MD, DCH, MPH†‖

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Abstract

Of 109 children admitted to a tertiary paediatric hospital with a diagnosis of invasive meningococcal disease from 2000–2011, 37.6% (n = 41) developed sequelae; for serogroup B, 41.3% developed sequelae. Independent predictors of sequelae included: fever ≥ 39°C on hospital presentation [odds ratio (OR): 4.5; P = 0.012] and a diagnosis of septicemia with meningitis compared with septicemia alone (OR: 15.5; P < 0.001) and meningitis alone (OR: 7.8; P = 0.002).

Copyright © 2013 by Lippincott Williams & Wilkins

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