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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3182a73ebb
HIV Reports

Prospective Cohort Study Comparing Seasonal and H1N1(2009) Pandemic Influenza Virus Illnesses in HIV-infected Children During 2009

Madhi, Shabir A. MBBCh, FCPaeds, PhD*†‡; Kuwanda, Locadiah MSc†‡; Venter, Marietjie PhD*; Violari, Avy FCPaeds§

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Abstract

A cohort of 410 young HIV-infected children was prospectively investigated for seasonal and A(H1N1p)2009 influenza virus illness during 2009. The incidence of confirmed illness due to seasonal influenza was 3-fold greater than A(H1N1p)2009 (0.7 vs. 0.2 per 100 child-weeks, respectively; P = 0.0001), and the clinical presentations were similar. Illnesses due to seasonal and A(H1N1p)2009 influenza were self-limiting without neuraminidase inhibitor therapy.

© 2014 by Lippincott Williams & Wilkins, Inc.

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