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Fatal Outcome of Rhino-orbital-cerebral Mucormycosis Due to Bilateral Internal Carotid Occlusion in a Child After Hematopoietic Stem Cell Transplantation

Abela, Lucia MD*; Toelle, Sandra P. MD*; Hackenberg, Annette MD*; Scheer, Ianina MD; Güngör, Tayfun MD; Plecko, Barbara MD*

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31829e69e7
Brief Reports
Abstract

Rhino-orbito-cerebral mucormycosis is a rare fulminant opportunistic fungal infection that particularly occurs in immunocompromised patients. We present a case of fatal invasive rhino-orbito-cerebral mucormycosis complicated by bilateral thrombotic occlusion of the internal carotid artery with consequent cerebral infarction in a 5-year-old boy after hematopoietic stem cell transplantation for acute pre–B-cell lymphoblastic leukemia

Author Information

From the Departments of *Neurology, Diagnostic Imaging and Immunology, University Children’s Hospital of Zurich, Zurich, Switzerland.

Accepted for publication May 29, 2013.

The authors have no funding or conflicts of interest to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com).

Address for correspondence: Barbara Plecko, MD, University Children’s Hospital, Steinwiesstrasse 75, CH-8032 Zurich, Switzerland. E-mail: Barbara.Plecko@kispi.uzh.ch.

© 2013 by Lippincott Williams & Wilkins, Inc.