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Prevalence of Mycobacteremia Among HIV-infected Infants and Children in Northern Tanzania

Gray, Katherine D. BE*; Cunningham, Coleen K. MD; Clifton, Dana C. MD; Afwamba, Isaac A. DipMLT; Mushi, Godfrey S. DipClinMed; Msuya, Levina J. MD¶‖; Crump, John A. MB, ChB, DTM&H‡§¶‖**; Buchanan, Ann M. MD, MPH, DTM&H†¶ **

Pediatric Infectious Disease Journal: July 2013 - Volume 32 - Issue 7 - p 754–756
doi: 10.1097/INF.0b013e318286957f
HIV Reports

Mycobacterium tuberculosis is a common cause of bloodstream infections among HIV-infected adults in sub-Saharan Africa, and is associated with high morbidity and mortality. We found no cases of mycobacteremia among 93 ill, HIV-infected children in northern Tanzania, despite optimization of laboratory methods and selection of patients thought to be at highest risk for disseminated infection.

From the *Duke University Medical Center, Durham, NC; Department of Pediatrics, Division of Infectious Diseases; Department of Medicine, Division of Infectious Diseases and International Health; §Department of Pathology, Duke University Medical Center, Durham, NC; Kilimanjaro Christian Medical Centre; Kilimanjaro Christian Medical College, Tumaini University, Moshi, Tanzania; and **Duke Global Health Institute, Duke University, Durham, NC.

Supported by Thrasher Research Fund (NR-0083 to A.M.B.); the International Studies on AIDS Associated Co-infections, United States National Institutes of Health (U01 AI062563 to C.K.C., I.A.A., G.S.M., L.J.M. and J.A.C.); the AIDS International Training and Research Program (D43 PA-03-018 to L.J.M., J.A.C. and I.A.A.); the Duke Clinical Trials Unit and Clinical Research Sites (U01 AI069484 to C.K.C., I.A.A., L.J.M., J.A.C. and A.M.B.); the Duke Center for AIDS Research (5P30 AI064518 to C.K.C., J.A.C. and A.M.B.); the Duke Global Institute of Health (K.D.G.) and the Stead-Duke Global Health Institute Research Scholars Program (K.D.G.). The authors have no other funding or conflicts of interest to disclose.

Address for correspondence: Ann M. Buchanan, MD, MPH, DTM&H, KCMC-Duke Collaboration, Box 3010, Moshi, Tanzania. E-mail: ann.buchanan@duke.edu.

© 2013 by Lippincott Williams & Wilkins, Inc.