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Exchange Blood Transfusion in the Management of Severe Pertussis in Young Infants

Nieves, Delma MD*; Bradley, John S. MD; Gargas, Jessie MD; Mason, Wilbert H. MD; Lehman, Deborah MD§; Lehman, Samuel M. MD; Murray, Erin L. PhD; Harriman, Kathleen PhD; Cherry, James D. MD, MSc**

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31828c3bb3
Brief Reports

We analyzed data from 10 young infants who received exchange blood transfusions for management of severe pertussis. Our data are insufficient to address efficacy of the procedure, but our data, as well as previous reports in the literature, indicate that if the procedure is to be successful, it should be done before organ failure has occurred and immediately if shock/hypotension occur.

Author Information

From the *Children’s Hospital of Orange County, Orange; Rady Children’s Hospital San Diego, San Diego; Children’s Hospital Los Angeles; §Cedars-Sinai Medical Center, Los Angeles; Children’s Hospital of Central California, Fresno; California Department of Public Health, Richmond; and **Mattel Children’s Hospital, University of California, Los Angeles, CA.

The authors have no funding or conflicts of interest to disclose.

Address for correspondence: James D. Cherry, MD, MSc, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, MDCC 22–442, Los Angeles, CA 90095–1752. E-mail:

© 2013 Lippincott Williams & Wilkins, Inc.