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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31828807a4
Brief Reports

Evaluation of IgG Anti-Toxoplasma Avidity and Polymerase Chain Reaction in the Postnatal Diagnosis of Congenital Toxoplasmosis

Torres, Elizabeth MSc; Rivera, Raul MSc; Cardona, Nestor MSc; Sanchez, Victor BSc; Lora, Fabiana MSc; Gómez-Marín, Jorge Enrique MD, PhD

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Confirmatory tests for congenital toxoplasmosis were evaluated in 23 infected and 31 uninfected newborns. Conventional polymerase chain reaction was better than real-time polymerase chain reaction, but did not identify additional cases. Avidity tests added 2 new cases that were not identified by other criteria. Overall sensitivity was 82.6%. Avidity assay, but not polymerase chain reaction, increased the sensitivity of confirmatory assays in congenital toxoplasmosis.

© 2013 Lippincott Williams & Wilkins, Inc.


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