We evaluated the accuracy and interobserver variation of 3 clinical decision rules for streptoccocal pharyngitis diagnosis. Oropharyngeal swab culture was the reference. The Abu Reesh rule had the highest sensitivity and the World Health Organization rule showed the highest specificity. The interobserver variation of those rules indicates the need for better training of clinicians.
From the *Laboratory of Clinical Epidemiology of the Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz; †Souza Marques Medical School; and ‡Prontobaby Hospital, Rio de Janeiro, Brazil.
This study was funded by the Technological Research and Development Program (PIPDT-2011) of the IPEC/FIOCRUZ and the Carlos Chagas Foundation of Research Support—FAPERJ (S.R.L.P. had a fellowship JCNE E-26/101–511/2010, and D.N. had a PIBIC CNPq scholarship.). The funding sources had no role in the following: study design and conduct; and data collection, analysis and interpretation. D.H.G.O. had full access to all data and final responsibility for the decision to submit for publication on behalf of all authors. The authors have no other funding or conflicts of interest to disclose.
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Address for correspondence: Dulce Helena Gonçalves Orofino, MSc, Laboratory of Clinical Epidemiology of the Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Avenida Brasil 4036 sala 301-A-Manguinhos, Rio de Janeiro, Brazil. E-mail: email@example.com.