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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3182847295
Brief Reports

Hospital-Based Surveillance for Rotavirus Gastroenteritis using Molecular Testing and Immunoassay During the 2011 Season in Botswana

Welch, Henry MD*†; Steenhoff, Andrew P. MD*†‡; Chakalisa, Unoda MD*; Arscott-Mills, Tonya MD*†‡; Mazhani, Loeto MD‡§; Mokomane, Margaret MSc; Foster-Fabiano, Sara BA; Wirth, Kathleen E. ScD**; Skinn, Andrew MD, PhD††; Pernica, Jeffrey M. MD‡‡; Smieja, Marek MD‡‡; Goldfarb, David M. MD*‡‡‡

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Abstract

We describe rotavirus testing and clinical characteristics for children admitted with acute gastroenteritis during Botswana's 2011 rotavirus season. The rotavirus season extended from June to October with rotavirus-specific case fatality being 2.8%. Using molecular testing as reference, the immunochromatographic test had a sensitivity of 76.5% and specificity of 68.0%. Rotavirus vaccine may significantly reduce childhood morbidity and mortality in Botswana.

© 2013 Lippincott Williams & Wilkins, Inc.

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