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Edith Lincoln, an American Pioneer of Childhood Tuberculosis

Donald, Peter R. FRCP, MD, FCP

Pediatric Infectious Disease Journal: March 2013 - Volume 32 - Issue 3 - p 241–245
doi: 10.1097/INF.0b013e31827d3d12
History of Medicine

Edith Lincoln (1899–1971), one of the most influential American pediatricians to study childhood tuberculosis, managed more than a thousand children from time of tuberculosis infection into adult life. She spoke with authority regarding the prognosis of childhood tuberculosis. Her observations of chemotherapy in children treated with isoniazid led directly to chemoprophylaxis, now of great importance in the management of the human immunodeficiency syndrome.

From the Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.

Accepted for publication November 24, 2012.

Supported by National Research Foundation of South Africa and the Desmond Tutu Tuberculosis Centre. The author has no other funding or conflicts of interest to disclose.

Address for correspondence: Peter R. Donald, FRCP, MD, FCP, Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 19063, Tygerberg 7505, South Africa. E-mail: prd@sun.ac.za.

© 2013 Lippincott Williams & Wilkins, Inc.