Skip Navigation LinksHome > December 2011 - Volume 30 - Issue 12 > Evolution of the Epidemiology of Pneumococcal Disease Among...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318232ee3e
Brief Reports

Evolution of the Epidemiology of Pneumococcal Disease Among Utah Children Through the Vaccine Era

Ampofo, Krow MB ChB*; Pavia, Andrew T. MD*; Stockmann, Chris R. BSc*; Blaschke, Anne J. MD, PhD*; Weng, Hsin Yi Cindy MS*; Korgenski, Kent E. MS*,†; Daly, Judy PhD*,†; Byington, Carrie L. MD*

Collapse Box


From 1996 to 2009, we analyzed changes in pneumococcal disease (PD) in Utah children aged <18 years using International Classification of Diseases, ninth revision coded hospital discharges. We observed a sustained decrease in the incidence of PD among children <5 years in 2001–2004 (−36%) and 2005–2009 (−34%) compared with 1996–2000 (pre-7-valent pneumococcal conjugate vaccine). Decreases were primarily in bacteremia, uncomplicated pneumonia, and meningitis. In contrast, significant increases in complicated pneumonia/empyema were noted in children <5 years (+95% and +85%) and 5 to 17 years (+2% and +70%). Despite decreases in PD among Utah children, complicated pneumonia/empyema has increased during the 7-valent pneumococcal conjugate vaccine era.

© 2011 Lippincott Williams & Wilkins, Inc.


Article Tools


Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.