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Echocardiography in Pediatric Infective Endocarditis

Penk, Jamie S. MD*; Webb, Catherine L. MD*; Shulman, Stanford T. MD*; Anderson, Evan J. MD*,†

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31822d320b
Brief Reports

Transesophageal echocardiography is more sensitive than transthoracic echocardiography (TTE) in detecting endocarditis in adults; however, pediatric data are limited. Retrospectively, 39 subjects with endocarditis were divided into adult-sized (≥60 kg) and pediatric-sized (<60 kg). TTE was 97% sensitive in pediatric-sized subjects but 70% in adult-sized subjects (P < 0.05). TTE is usually sufficient for detection of endocarditis in children <60 kg.

Author Information

From the Departments of *Pediatrics and †Medicine, Children's Memorial Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL.

Accepted for publication July 11, 2011.

No direct support was received for writing this article.

Dr. Anderson has previously served on the speaker's bureau for Merck, has consulted for both Merck and GlaxoSmithKline, and has received research support from Merck, and Meridian Bioscience, Inc and financial compensation for Medscape CME. Dr. Shulman has previously served on the speaker's bureau for both Merck and GlaxoSmithKline and has served on an advisory board for Merck vaccines and Novartis vaccines. He is currently the chairman of a Data Safety and Monitoring Committee for Pfizer. The authors have no other funding or conflicts of interest to disclose.

Address for correspondence: Jamie S. Penk, MD, Department of Critical Care, Room M 4811, 111 Michigan Ave NW, Washington, DC 20010. E-mail:

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© 2011 Lippincott Williams & Wilkins, Inc.