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Central Venous Catheter-related Blood Stream Infections in Children Undergoing Hematopoietic Stem Cell Transplant for Primary Immunodeficiency and Other Nonmalignant Disorders

Cole, Theresa S. BM*; Rogerson, Elizabeth; Collins, Jennifer Csi; Galloway, Angela MB BS; Clark, Julia BMBS, BMedSci

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31822940a8
Brief Reports
Abstract

A single-center experience of catheter-related blood stream infections in children undergoing hematopoietic stem cell transplant for primary immunodeficiency is described. The rate of definite central venous catheter infections was 5.31/1000 line days. Staphylococcus epidermidis was the most commonly identified organism. Teicoplanin resistance occurred in 17% of S. epidermidis infections. The central catheter was removed in 21% of infections.

Author Information

From the *Institute of Cellular Medicine, Newcastle University, Newcastle, United Kingdom; †Paediatric Immunology & Infectious Diseases Department, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle, United Kingdom; and ‡Microbiology Department, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle, United Kingdom.

Accepted for publication June 14, 2011.

The authors have no funding or conflicts of interest to disclose.

Address for correspondence: Theresa S. Cole, BM, Paediatric Immunology & Infectious Diseases Department, Old Children's Outpatients, Royal Victoria Infirmary, Newcastle, NE1 4LP, United Kingdom. E-mail: theresa.cole@ncl.ac.uk.

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© 2011 Lippincott Williams & Wilkins, Inc.