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Prevalence of Lyme Meningitis in Children With Aseptic Meningitis in a Lyme Disease-endemic Region

Garro, Aris C. MD, MPH*; Rutman, Maia S. MD*; Simonsen, Kari MD†; Jaeger, Jenifer L. MD†; Chapin, Kimberle MD‡; Lockhart, Gregory MD*

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e31822e8e68
Brief Reports
Abstract

This study determined the prevalence of Lyme meningitis in children with undifferentiated aseptic meningitis from April to December in a Lyme disease-endemic region. Of the 60 children, 8 were seropositive (prevalence 13.3%; 95% confidence interval: 6.3–25.1%), with another probable case having high cerebrospinal fluid antibody titers. Clinicians in endemic regions should evaluate children with undifferentiated aseptic meningitis for Lyme meningitis in appropriate seasons.

Author Information

From the *Division of Pediatric Emergency Medicine, Department of Emergency Medicine, Rhode Island Hospital and Warren Alpert School of Medicine of Brown University, Providence, RI; †Division of Pediatric Infectious Disease, Department of Pediatrics, Rhode Island Hospital and Warren Alpert School of Medicine of Brown University, Providence, RI; and ‡Department of Pathology, Lifespan Academic Medical Centers, Providence, RI.

Accepted for publication May 31, 2011.

Kari Simonsen is currently at the Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE. Maia S. Rutman is currently at the Department of Pediatrics and Section of Emergency Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

There was no extramural financial support for this investigation or manuscript development. Intramural support was provided by the University Emergency Medicine Foundation at Rhode Island Hospital.

The authors have no conflicts of interest or funding to disclose.

Address for correspondence: Aris C. Garro, MD, MPH, Pediatric Emergency Medicine, Rhode Island Hospital, Coro East Building, Suite 160, Providence, RI 02903. E-mail: agarro@lifespan.org.

© 2011 by Lippincott Williams & Wilkins, Inc.