The efficacy of prednisolone in acute wheezing associated with human bocavirus infection was investigated in 232 hospitalized children (median age, 1.6 years). Clinical history, atopy status, and viral etiology were carefully studied. Outcomes included hospitalization time, duration of symptoms, and occurrence of relapses. No efficacy of prednisolone was found in children with serologically confirmed acute human bocavirus infection.
SUPPLEMENTAL DIGITAL CONTENT IS AVAILABLE IN THE TEXT.
From the *Department of Pediatrics, Turku University Hospital, Turku, Finland; †Department of Virology, Haartman Institute, University of Helsinki, Helsinki, Finland; ‡Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden; and §Department of Virology, University of Turku, Turku, Finland.
Accepted for publication October 28, 2010.
Supported by the Academy of Finland, the Finnish Cultural Foundation, the Turku University Foundation, the Foundation for Pediatric Research, and the Paulo Foundation.
Prednisolone and placebo were provided by Oy Leiras Finland Ab, Helsinki, Finland.
Address for correspondence: Tuomas Jartti, MD, Department of Pediatrics, Turku University Hospital, PO Box 52, FIN-20520 Turku, Finland. E-mail: firstname.lastname@example.org.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.pidj.com).