Skip Navigation LinksHome > February 2011 - Volume 30 - Issue 2 > INCIDENCE OF INFLUENZA VIRUS INFECTION IN EARLY INFANCY: A P...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181f63c39
Brief Reports

INCIDENCE OF INFLUENZA VIRUS INFECTION IN EARLY INFANCY: A PROSPECTIVE STUDY IN SOUTH ASIA

Henkle, Emily MPH, PhD*; Steinhoff, Mark C. MD*†; Omer, Saad B. MB BS, PhD‡; Roy, Eliza DCh§; Arifeen, Shams E. MB BS, DrPH§; Raqib, Rubhana PhD§; McNeal, Monica MS†; Breiman, Robert F. MD¶; Moss, William J. MD*; Zaman, K. MB BS, PhD§

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Abstract

We evaluated infant sera from an immunization trial in Bangladesh to assess influenza hemagglutination inhibition antibody titer increases in 131 unimmunized infants from birth to 6 months. We detected 31 serologically defined infections. Combined with 10 additional rapid test-proven influenza cases, the minimal estimated incidence was 31 of 100 infants (95% CI: 24–41). These data suggest a high burden of influenza in young infants in tropical South Asia.

© 2011 Lippincott Williams & Wilkins, Inc.

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