A CLUSTER OF PEDIATRIC ENDEMIC TYPHUS CASES IN ORANGE COUNTY, CALIFORNIAGreen, Jennifer S. MD*; Singh, Jasjit MD†; Cheung, Michele MD‡ ; Adler-Shohet, Felice C. MD†; Ashouri, Negar MD†Pediatric Infectious Disease Journal: February 2011 - Volume 30 - Issue 2 - pp 163-165 doi: 10.1097/INF.0b013e3181f4cc25 Brief Reports Abstract Author Information Murine typhus is typically a mild febrile illness caused by Rickettsia typhi, generally confined to Texas and Southern California. Clinicians should consider early treatment with doxycycline when presented with a child having protracted fever, rash, and headache. We present 5 pediatric cases and a literature review highlighting the changing epidemiology and diagnostic difficulty of typhus. From the Divisions of *Academic Affairs and †Infectious Disease, Children's Hospital of Orange County, Orange, CA; ‡Department of Public Health, County of Orange Health Care Agency, Orange, CA. Accepted for publication July 27, 2010. Address for correspondence: Jennifer Green, MD, Children's Hospital of Orange County, 455 S. Main St., Orange, CA 92686. E-mail: firstname.lastname@example.org. © 2011 Lippincott Williams & Wilkins, Inc.