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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181f42bb6
Brief Reports

STREPTOCOCCUS PNEUMONIAE NASOPHARYNGEAL COLONIZATION IN CHILDREN IN BRASOV, CENTRAL ROMANIA: HIGH ANTIBIOTIC RESISTANCE AND COVERAGE BY CONJUGATE VACCINES

Falup-Pecurariu, Oana MD*; Bleotu, Laura MD*; Zavarache, Cristina MD*; Peled, Nechama MSc†‡; Anton, Oana MD*; Robu, Michaela MD*; Falup-Pecurariu, Cristian MD*; Rogozea, Liliana MD*; Porat, Nurith MD‡§; Greenberg, David MD‡§; Dagan, Ron MD‡§; Leibovitz, Eugene MD‡§

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Abstract

We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.

© 2011 Lippincott Williams & Wilkins, Inc.

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