We report high colonization rates among 400 healthy infants and children, and moderate (66%) coverage by PCV7 and PCV10, with a superior (80%) PCV13 coverage. Most frequent serotypes were 23F, 6B, 19F, and 14. Resistance to penicillin, ceftriaxone, erythromycin, and trimethoprim/sulfamethoxazole was 83%, 18%, 62%, and 66%, respectively. 67% isolates were multidrug resistant. Pneumococcal conjugate vaccines covered 80% to 93% of multidrug resistant isolates.
From the *Department of Pediatrics, Children's Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania; †Clinical Microbiology Laboratories, Soroka University Medical Center, Beer-Sheva, Israel; ‡Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel; and §Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer-Sheva, Israel.
Accepted for publication July 20, 2010.
Supported by an ESPID Grant Award.
Address for correspondence: Eugene Leibovitz, MD, Pediatric Infectious Disease Unit, Soroka University Medical Center, PO Box 151, Beer-Sheva 84101, Israel. E-mail: firstname.lastname@example.org.