Skip Navigation LinksHome > December 2010 - Volume 29 - Issue 12 > SUSTAINED PROTECTION FROM PENTAVALENT ROTAVIRUS VACCINATION...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181ed18ab
Brief Reports

SUSTAINED PROTECTION FROM PENTAVALENT ROTAVIRUS VACCINATION DURING THE SECOND YEAR OF LIFE AT A LARGE, URBAN UNITED STATES PEDIATRIC HOSPITAL

Boom, Julie A. MD*†‡; Tate, Jacqueline E. PhD§; Sahni, Leila C. MPH*‡; Rench, Marcia A. BSN*†; Quaye, Osbourne PhD§; Mijatovic-Rustempasic, Slavica MSc§; Patel, Manish M. MD, MSc§; Baker, Carol J. MD*†¶; Parashar, Umesh D. MB BS, MPH§

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Abstract

Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children ≥12 months of age.

© 2010 by Lippincott Williams & Wilkins, Inc.

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