Share this article on:

Substantial Morbidity for Hospitalized Children With Community-Acquired Rotavirus Infections: 2005–2007 IMPACT Surveillance in Canadian Hospitals

Le Saux, Nicole MD*; Bettinger, Julie A. PhD; Halperin, Scott A. MD; Vaudry, Wendy MD§; Scheifele, David W. MDfor Members of the Canadian Immunization Monitoring Program, Active (IMPACT)

The Pediatric Infectious Disease Journal: September 2010 - Volume 29 - Issue 9 - p 879-882
doi: 10.1097/INF.0b013e3181e20c94
Brief Reports

We describe community-acquired rotavirus illness in 1359 children hospitalized at 12 centers in Canada between January 2005 and December 2007. The median age was 1.5 years. Almost half (48.6%) had significant dehydration, almost one-fifth (19%) had clinical sepsis and 7% had seizures at presentation. The median hospital stay was 3.4 days. Severe clinical presentations are less commonly described in surveillance programs.

From the *Division of Infectious Diseases, CHEO Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; †Vaccine Evaluation Center, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada; ‡Canadian Center for Vaccinology, IWK Health Center and Dalhousie University, Halifax, Nova Scotia, Canada; and §Stollery Children's Hospital and University of Alberta, Edmonton, Alberta, Canada.

Accepted for publication March 25, 2010.

Supported by a grant from GlaxoSmithKline Inc, Merck Canada and the Public Health Agency of Canada's Centre for Food-borne, Environmental and Zoonotic Infectious Diseases and Centre for Immunization and Respiratory Infectious Diseases.

Presented at the International Congress of Chemotherapy and Infection; June 18-21, 2009; Toronto, Ontario, Canada.

Address for correspondence: Nicole Le Saux, MD, FRCP(C), Division of Infectious Diseases, Children's Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1S 3C4, Canada. E-mail: lesaux@cheo.on.ca.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.pidj.com).

© 2010 Lippincott Williams & Wilkins, Inc.