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TRENDS IN HOSPITALIZATIONS FROM ALL-CAUSE GASTROENTERITIS IN CHILDREN YOUNGER THAN 5 YEARS OF AGE IN BRAZIL BEFORE AND AFTER HUMAN ROTAVIRUS VACCINE INTRODUCTION, 1998–2007

Lanzieri, Tatiana Miranda MD, MSc*; Costa, Iolanda MD†; Shafi, Fakrudeen A. MSc‡; Cunha, Maria Helena MD, MPH†; Ortega-Barria, Eduardo MD*; Linhares, Alexandre C. MD, PhD§; Colindres, Romulo E. MD, MPH*

Pediatric Infectious Disease Journal: July 2010 - Volume 29 - Issue 7 - pp 673-675
doi: 10.1097/INF.0b013e3181da8f23
Brief Reports

Rotavirus vaccination was introduced in Brazil in March 2006. We describe trends in hospitalizations from all-cause gastroenteritis in children younger than 5 years during pre- and postvaccination periods using hospital discharge data from Brazil Hospital Information System (SIH-SUS). A reduction in gastroenteritis hospitalizations of 26% and 48% in 2006 and in 2007, respectively, was observed among children younger than 1 year compared with prevaccination period (1998–2005). The largest reduction rates among children younger than 1 year were noted in the South and Southeast regions, approximately 56% in 2007, where vaccine coverage was the highest.

From the *GlaxoSmithKline Biologicals, Rio de Janeiro, Brazil; †Secretaria de Estado de Saúde do Estado do Pará, Belém, Brazil; ‡GlaxoSmithKline Biologicals, Bangalore, India; and §Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, Pará, Brazil.

Accepted for publication February 7, 2010.

Address for correspondence: Tatiana M. Lanzieri, MD, MSc, GlaxoSmithKline Brazil, Estrada dos Bandeirantes, 8464-22783-110, Rio de Janeiro, Brazil. E-mail: tatiana.m.lanzieri@gsk.com.

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© 2010 Lippincott Williams & Wilkins, Inc.