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POSTVACCINATION THROMBOCYTOPENIA IN CANADA

Sauvé, Laura J. MD, MPH*; Bettinger, Julie PhD*; Scheifele, David MD*; Halperin, Scott MD†; Vaudry, Wendy MD‡; Law, Barbara MD§; the members of the Canadian Immunization Monitoring Program, and Active (IMPACT)

Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181d2bb45
Brief Reports
Abstract

Active surveillance data from 12 Canadian tertiary-care hospitals on children hospitalized with postvaccination thrombocytopenia were analyzed. Since 1992, there have been 107 cases reported; while 96% of the children were symptomatic, only 2 had severe bleeding. With treatment, 28 children (26%) had normal platelet counts on discharge from hospital and 93% had documented recovery within 3 months.

Author Information

From the *Vaccine Evaluation Center, BC Children's Hospital and the University of British Columbia, Vancouver, British Columbia, Canada; †Canadian Center for Vaccinology, IWK Health Center and Dalhousie University, Halifax, Nova Scotia, Canada; ‡Division of Infectious Diseases, Department of Pediatrics, Stollery Children's Hospital and University of Alberta, Edmonton, Alberta, Canada; and §Centre for Immunization and Respiratory Infectious Diseases Division, Surveillance and Outbreak Response Division, Public Health Agency of Canada, Ottawa, Ontario, Canada.

Accepted for publication January 5, 2010.

The Canadian Immunization Monitoring Program, Active (IMPACT), is a national surveillance initiative funded by Public Health Agency of Canada, managed by the Canadian Pediatric Society and conducted by the IMPACT network of pediatric investigators.

Address for correspondence: Laura Sauvé, MD, MPH, Vaccine Evaluation Center, BC Children's Hospital, 950 West 28th Avenue, Vancouver, British Columbia, Canada V5Z 4H4. E-mail: lsauve@cw.bc.ca.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.pidj.com).

© 2010 Lippincott Williams & Wilkins, Inc.