Skip Navigation LinksHome > June 2010 - Volume 29 - Issue 6 > HOSPITALIZATIONS FOR INVASIVE PNEUMOCOCCAL DISEASE AMONG HUM...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181cfb65f
Brief Reports

HOSPITALIZATIONS FOR INVASIVE PNEUMOCOCCAL DISEASE AMONG HUMAN IMMUNODEFICIENCY VIRUS-1 INFECTED CHILDREN, ADOLESCENTS AND YOUNG ADULTS IN THE UNITED STATES IN THE ERA OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY AND THE CONJUGATE PNEUMOCOCCAL VACCINE

Kourtis, Athena P. MD, PhD*; Ellington, Sascha MSPH*; Bansil, Pooja MPH†; Jamieson, Denise J. MD, MPH*; Posner, Samuel F. PhD*

Collapse Box

Abstract

We describe hospitalization trends of invasive pneumococcal disease (IPD) among human immunodeficiency virus-infected individuals <25 years of age since the introduction of highly active antiretroviral therapy (HAART) and the 7-valent pneumococcal conjugate vaccine (PCV7) in the United States, using the Nationwide Inpatient Sample. We estimated national trends of IPD hospitalizations during 3 periods: 1994 to 1995 (pre-HAART and pre-PCV7 era); 1998 to 1999 (HAART and pre-PCV7 era); and 2004 to 2005 (HAART and early PCV7 era). The number of IPD hospitalizations among human immunodeficiency virus-infected children and youth <25 years in the United States declined by 78.7% between 1994/1995 and 2004/2005 (P = 0.03). This decrease was more pronounced among younger children.

© 2010 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Article Level Metrics

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.