A fluoroquinolone-resistant Escherichia coli strain of sequence type ST131 caused severe septic arthritis and contiguous osteomyelitis in an 8-month-old girl, and colonized the girl's healthy mother, who shared a different fecal E. coli strain with the father. Within-household transmission can contribute to the dissemination of the emerging, multidrug-resistant ST131 clonal group, which has evident invasive potential for otherwise-healthy children.
From the *Infectious Diseases Section, Veterans Affairs Medical Center, Minneapolis, MN; †Department of Medicine, University of Minnesota, Minneapolis, MN; ‡Orthopaedic Surgery Department, Children's Mercy Hospital, Kansas City, MO; and §Department of Child Health, University of Missouri School of Medicine, Columbia, MO.
Accepted for publication October 30, 2009.
Supported by Office of Research and Development, Medical Research Service, Department of Veterans Affairs (J.R.J.).
Address for correspondence: James R. Johnson, MD, Infectious Diseases (111F), VA Medical Center, Minneapolis, MN 55417. E-mail: firstname.lastname@example.org.
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