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SEQUENCE TYPES AND ANTIMICROBIAL SUSCEPTIBILITY OF INVASIVE STREPTOCOCCUS PNEUMONIAE ISOLATES FROM A REGION WITH HIGH ANTIBIOTIC SELECTIVE PRESSURE AND SUBOPTIMAL VACCINE COVERAGE

Janapatla, Rajendra-Prasad PhD; Hsu, Mei-Hua MS; Du, Jia-Fu BS; Hsieh, Yu-Chia MD; Lin, Tzou-Yien MD; Chiu, Cheng-Hsun MD, PhD

The Pediatric Infectious Disease Journal: May 2010 - Volume 29 - Issue 5 - p 467-469
doi: 10.1097/INF.0b013e3181cb45f3
Brief Reports

Multilocus sequence typing was carried out on 95 invasive pneumococcal isolates belonging to the most common 7 serotypes currently circulating in Taiwan. The study confirmed continued prevalence in Taiwan of a few global clones and sequence types (STs) since the mid-1990s and identified the recent emergence of ST320 (19A) and ST902 (6A). Antimicrobial nonsusceptibility was common in the predominant STs of serotypes 14, 19A, 19F, and 23F.

From the Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Accepted for publication November 5, 2009.

Address for correspondence: Cheng-Hsun Chiu, MD, PhD, Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, 5 Fu-Hsin Street, Kweishan, Taoyuan 333, Taiwan. E-mail: chchiu@adm.cgmh.org.tw.

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© 2010 Lippincott Williams & Wilkins, Inc.