Skip Navigation LinksHome > May 2010 - Volume 29 - Issue 5 > HEPATITIS B VIRUS DNA IN SALIVA FROM CHILDREN WITH CHRONIC H...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181d8e009
Brief Reports

HEPATITIS B VIRUS DNA IN SALIVA FROM CHILDREN WITH CHRONIC HEPATITIS B INFECTION: IMPLICATIONS FOR SALIVA AS A POTENTIAL MODE OF HORIZONTAL TRANSMISSION

Heiberg, Ida Louise MD*; Hoegh, Mette MSc, PhD†; Ladelund, Steen MSc‡; Niesters, Hubert G. M. MD, DMSc§; Hogh, Birthe MD, DMSc*

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Abstract

To explore the mechanism of horizontal transmission of hepatitis B virus (HBV) among children, we investigated the quantitative relationship between HBV in saliva and blood from 46 children with chronic hepatitis B.

We found high levels of HBV DNA in saliva of HBeAg (+) children, suggesting saliva as a vehicle for horizontal transmission of HBV among children.

© 2010 Lippincott Williams & Wilkins, Inc.

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