Skip Navigation LinksHome > April 2010 - Volume 29 - Issue 4 > HUMAN RHINOVIRUS CAUSES SEVERE INFECTION IN PRETERM INFANTS
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181c6e60f
Brief Reports

HUMAN RHINOVIRUS CAUSES SEVERE INFECTION IN PRETERM INFANTS

van Piggelen, Renée O. MD*; van Loon, Anton M. PhD†; Krediet, Tanette G. MD, PhD*; Verboon-Maciolek, Malgorzata A. MD, PhD*

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Abstract

Data of 11 infants (median gestational age and birth weight 30 weeks and 1520 g, respectively) with severe human rhinovirus infection (HRV) are described. Nine of 11 (82%) were preterm infants and 7 of these 9 (78%) became infected during their stay in the neonatal intensive care unit. All infants presented with respiratory distress and all needed respiratory support for a median of 6 days. Radiologic findings included perihilar streakiness, atelectasis, focal consolidation, and hyperinflation. The diagnosis of HRV infection was made by real-time polymerase chain reaction in nasopharyngeal aspirate. All infants recovered from their HRV infection. HRV can cause severe disease in preterm infants requiring respiratory support.

© 2010 Lippincott Williams & Wilkins, Inc.

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