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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181c6f05c
Brief Reports

CLINICAL PERFORMANCE OF A RAPID INFLUENZA TEST AND COMPARISON OF NASAL VERSUS THROAT SWABS TO DETECT 2009 PANDEMIC INFLUENZA A (H1N1) INFECTION IN THAI CHILDREN

Suntarattiwong, Piyarat MD*; Jarman, Richard G. PhD†; Levy, Jens PhD‡; Baggett, Henry C. MD, MPH§; Gibbons, Robert V. MD, MPH†; Chotpitayasunondh, Tawee MD, DTM&H*; Simmerman, James M. PhD, RN‡

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Abstract

We identified febrile pediatric outpatients seeking care for influenza like illness in Bangkok. Two nasal and 1 throat swab were tested using the QuickVue A+B rapid influenza kit and reverse transcription-polymerase chain reaction. Among 142 pandemic influenza A (H1N1)-positive patients, the QuickVue test identified 89 positive tests for a sensitivity of 62.7% (95% confidence interval [CI]: 54.7–70.6). Specificity was 99.2% (95% CI: 98–100). In the 0 to 2 years age group, sensitivity was 76.7% (95% CI: 61.5–91.8). Throat and nasal swabs are equally useful diagnostic specimens for reverse transcription-polymerase chain reaction diagnosis.

© 2010 Lippincott Williams & Wilkins, Inc.

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