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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181be9f9c
Brief Reports

TEST CHARACTERISTICS OF COMMERCIAL INFLUENZA ASSAYS FOR DETECTING PANDEMIC INFLUENZA A (H1N1) IN CHILDREN

Sandora, Thomas J. MD, MPH*; Smole, Sandra C. PhD†; Lee, Grace M. MD, MPH*‡; Chung, Sarita MD§; Williams, Laura BS¶; McAdam, Alexander J. MD, PhD¶

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Abstract

We assessed the test characteristics of 2 influenza antigen tests, a rapid immunoassay and a direct fluorescence antibody (DFA) assay, in detecting pandemic influenza A (H1N1) in children up to 18 years of age, using polymerase chain reaction as the standard. The sensitivities of BinaxNOW (59.6%) and direct fluorescence antibody (57.3%) were similar. The specificity of each test was >99%.

© 2010 Lippincott Williams & Wilkins, Inc.

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