Skip Navigation LinksHome > January 2010 - Volume 29 - Issue 1 > Ureaplasma: Pathogen or Passenger in Neonatal Meningitis?
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181b21016
Instructive Cases

Ureaplasma: Pathogen or Passenger in Neonatal Meningitis?

Clifford, Vanessa MB BS, BMedSc, MA, MPH*; Tebruegge, Marc DTM&H, DLSHTM, MRCPCH, MSc, MD*†‡; Everest, Neil MB BS, BSc, DRCOG§; Curtis, Nigel MA, MB BS, DCH, DTM&H, FRCPCH, PhD*†‡

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Abstract

The significance of Ureaplasma species as pathogens in neonatal meningitis remains contentious. Using an illustrative case of a premature infant with Ureaplasma parvum meningitis, confirmed by cerebrospinal fluid cultures and both specific and 16s rDNA polymerase chain reaction, we discuss the epidemiology of Ureaplasma species, the difficulties involved in diagnosis and establishing pathogenicity, and the challenges in defining appropriate treatment.

© 2010 Lippincott Williams & Wilkins, Inc.

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