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Faden, Dara BA; Faden, Howard S. MD
Forty-five children treated with 82 courses of 15 different antibiotics over 344 weeks during outpatient parenteral antibiotic therapy were evaluated for adverse drug events (ADE). Fifty-one percent of the courses had an associated ADE and 32.5% of the antibiotic courses were discontinued because of ADE. Vancomycin had the highest ADE rate at 85.7% and ceftriaxone had the highest ADE-related discontinuation rate at 66.7%. Cefazolin had the lowest rate of ADE and ADE-related discontinuation rates at 0% for both.
© 2009 Lippincott Williams & Wilkins, Inc.
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outpatient parenteral antibiotic therapy, adverse drug reactions, vancomycin, ceftriaxone, oxacillin, clindamycin, cefazolin, drug-related leukopenia, drug-related hepatitis, drug-related rash
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