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CLINICAL AND MICROBIOLOGIC CHARACTERISTICS OF GROUP A STREPTOCOCCAL NECROTIZING FASCIITIS IN CHILDREN

Minodier, Philippe MD*†; Bidet, Philippe MD; Rallu, Fabien PhD§; Tapiero, Bruce MD, FRCP(C)*; Bingen, Édouard PhD; Ovetchkine, Philippe MD*

The Pediatric Infectious Disease Journal: June 2009 - Volume 28 - Issue 6 - p 541-543
doi: 10.1097/INF.0b013e318195bb10
Brief Reports

An increase in the incidence of Group A streptococcal necrotizing fasciitis has recently been observed in Montréal, Canada. Clinical features of children hospitalized for invasive Group A streptococcal infections and various virulence factor genes of the bacteria were concomitantly analyzed. It was determined that varicella and presence of speC gene in group A streptococcal strains were associated with necrotizing fasciitis.

From the *Infectious Diseases Division, Department of Pediatrics, CHU Sainte-Justine, Montréal, Canada; †Pediatric Emergency, CHU Nord, Chemin des Bourrelly, 13015 Marseille, France; ‡Department of Microbiology, Robert Debré Hospital, Paris, France; and §Department of Microbiology and Immunology, CHU Sainte-Justine, Montréal, Canada.

Accepted for publication November 18, 2008.

Supported by the Association pour le Développement de la Recherche Médicale (ADEREM), Marseille, France (to P.M.).

Address for correspondence: Philippe Ovetchkine, MD, Infectious Diseases Division, Department of Pediatrics, CHU Sainte-Justine-Université de Montréal, 3175 Côte Sainte-Catherine, Montréal (Qc), Canada H3T 1C5. E-mail: philippe.ovetchkine@umontreal.ca.

© 2009 Lippincott Williams & Wilkins, Inc.