Skip Navigation LinksHome > May 2009 - Volume 28 - Issue 5 > MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS A...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e318193ead7
Brief Reports

MATERNALLY DERIVED ANTIBODIES AGAINST BORDETELLA PERTUSSIS ANTIGENS PERTUSSIS TOXIN AND FILAMENTOUS HEMAGGLUTININ IN PRETERM AND FULL TERM NEWBORNS

Heininger, Ulrich MD*; Riffelmann, Marion MD†‡; Leineweber, Birgit MD*; Wirsing von Koenig, Carl Heinz MD†‡

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Abstract

We measured IgG-anti–pertussis toxin and –IgG-anti–filamentous hemagglutinin antibody values in 43 full term and 34 preterm infants and 79 mothers. Antibody values were generally low and mean values were higher in full term than preterm infants. Transfer ratios increased with gestational age of the newborns. Based on these findings, maternal and neonatal immunization strategies should be considered to protect young infants from pertussis.

© 2009 Lippincott Williams & Wilkins, Inc.

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