Skip Navigation LinksHome > May 2009 - Volume 28 - Issue 5 > DAPTOMYCIN THERAPY FAILURE IN AN ADOLESCENT WITH METHICILLIN...
Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181927891
Brief Reports

DAPTOMYCIN THERAPY FAILURE IN AN ADOLESCENT WITH METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS BACTEREMIA

Jacobson, Lara M. MD*; Milstone, Aaron M. MD†; Zenilman, Jonathan MD‡; Carroll, Karen C. MD§; Arav-Boger, Ravit MD†

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Abstract

Daptomycin is a Food and Drug Administration-approved alternative to vancomycin for the treatment of serious methicillin-resistant Staphylococcus aureus infections in adults. Treatment failure with daptomycin is increasingly reported in adults, but data in children are limited. We report an adolescent patient with severe burn injuries who had persistent methicillin-resistant Staphylococcus aureus bacteremia and rapidly developed nonsusceptibility to daptomycin. We review the relevant literature.

© 2009 Lippincott Williams & Wilkins, Inc.

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