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Pediatric Infectious Disease Journal:
doi: 10.1097/INF.0b013e3181945999
Instructive Case

Peripheral Neuropathy in an Adolescent Treated With Linezolid

Linam, W Matthew MD*†; Wesselkamper, Kristen MD‡; Gerber, Michael A. MD*

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Abstract

The increased incidence of methicillin-resistant Staphyloccocus aureus infections may increase linezolid use in children. Peripheral neuropathy is a rare adverse effect of linezolid therapy and is more frequent with prolonged courses. We present an adolescent with peripheral neuropathy after 4 months of linezolid therapy and review the literature related to linezolid-induced neuropathies. Children receiving long-term linezolid therapy should be monitored for neuropathy.

© 2009 Lippincott Williams & Wilkins, Inc.

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